英语邮件的开头和结尾是建立专业形象的关键部分，以下是具体建议：

一、邮件开头

问候语

- 直接表达：

How is everything？ / I hope everything is all right. / How are you getting along these days？

- 特殊场景：It’s a long time since we last met. / I have been missing you a lot since we met last time.

感谢表达

- Thank you for your letter of September 1.

- Many thanks for your kind letter which reached me yesterday.

- I am grateful for your support.

引入主题

- I am writing to inform you about... / I would like to request your assistance with...

商务邮件专用

- On behalf of..., I have the honor to invite you to...

二、邮件结尾

表达期待

- I am looking forward to receiving your letter.

- I eagerly await your response.

感谢与礼貌

- Thank you in advance.

- Please write to me as soon as possible.

商务邮件专用

- Sincerely, / Best regards,

- Kind regards,

三、注意事项

称呼：

若收件人姓名未知，使用Dear Sir/Madam；若知道性别，使用Dear Mr./Ms. ；熟悉后可用First Name + Last Name。

格式：每封邮件应包含主题行，正文与结尾需空一行。

避免错误：如"Please wirte to me"应为"Please write to me"。

通过合理使用这些开头和结尾，可以提升邮件专业度，减少沟通成本。