世界上最长且最难的句子之一出现在詹姆斯·乔伊斯（James Joyce）的名著《尤利西斯》（Ulysses）中。在《尤利西斯》的第十八章，有一个非常长的句子，如果按八句算，那么最长的句子有4391个词；如果按两句算，那么最长的句子有12931个词。这个句子非常复杂，包含了大量的词汇和深刻的哲学思考。

此外，虽然其他一些句子也因其长度和复杂性而著称，例如：

1. "It was a discovery that had been subtly altering the情趣 of his mind for years, a revelation that was gradually making him a different sort of animal, but an animal with more of what we call human consciousness than he had ever had before."

2. "The reasonable man adapts himself to the world； the unreasonable one persists in trying to adapt the world to himself. Therefore, all progress depends on the unreasonable man."

3. "It is a far, far better thing that I do than I have ever done； it is a far, far better rest that I go to than I have ever known."

但这些句子在长度和复杂性上都无法与《尤利西斯》中的那个句子相比。